Jaroslav Chladek: search on Z-Library

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1

Pharmacokinetics and Pharmacodynamics of Methotrexate in Non-Neoplastic Diseases

Dr Jiří Grim, Jaroslav Chládek, Jiřina Martínková

Journal:

Clinical Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 151 KB

english, 2003

2

An improved high-performance liquid chromatography method for quantification of methotrexate polyglutamates in red blood cells of children with juvenile idiopathic arthritis

Miloš Hroch, Jana Tuková, Pavla Doležalová, Jaroslav Chládek

Journal:

Biopharmaceutics & Drug Disposition

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

3

High-dose methotrexate in children with acute lymphoblastic leukemia: 7-hydroxymethotrexate systemic exposure and urinary concentrations at the steady state correlate well with those of methotrexate

Chládková, Jiřina, Hak, Jiří, Martínková, Jiřina, Chládek, Jaroslav

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 241 KB

english, 2011

4

Adenoid hypertrophy affects screening for primary ciliary dyskinesia using nasal nitric oxide

Rybnikar, Tomas, Senkerik, Marian, Chladek, Jaroslav, Chladkova, Jirina, Kalfert, David, Skoloudik, Lukas

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

2018

Language:

english

File:

PDF, 723 KB

english, 2018

5

No Effect of Phenobarbital Pretreatment of Rats on Methotrexate Pharmacokinetics in the Isolated Liver Perfused in a Single-Pass Way

Chládek, Jaroslav, Martínková, Jiřina, Šišpera, Luděk, Chládková, Jiřina, Cermanová, Jolana

Journal:

Year:

2001

Language:

english

File:

PDF, 183 KB

english, 2001

6

Pharmacokinetics and tissue distribution of platinum in rats following single and multiple oral doses of LA-12 [(OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV)]

Petr Sova, Jaroslav Chladek, Frantisek Zak, Adolf Mistr, Ales Kroutil, Martin Semerad, Zdenek Slovak

Journal:

International Journal of Pharmaceutics

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

7

Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

Hroch, Miloš, Mičuda, Stanislav, Cermanová, Jolana, Chládek, Jaroslav, Tomšík, Pavel

Journal:

Journal of Chromatography B

Year:

2013

Language:

english

File:

PDF, 803 KB

english, 2013

8

Nitrite in exhaled breath condensate as a marker of nitrossative stress in the airways of patients with asthma, COPD, and idiopathic pulmonary fibrosis

Vladimír Rihák, Petr Zatloukal, Jirina Chládková, Alena Zimulová, Zuzana Havlínová, Jaroslav Chládek

Journal:

Journal of Clinical Laboratory Analysis

Year:

2010

Language:

english

File:

PDF, 111 KB

english, 2010

9

Tolerability and Outcomes of Kinetically Guided Therapy With Gentamicin in Critically Ill Neonates During the First Week of Life: An Open-Label, Prospective Study

Jirina Martínková, Pavla Pokorná, Jiri Záhora, Jaroslav Chládek, Václav Vobruba, Iva Selke-Krulichová, Jirina Chládková

Journal:

Clinical Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

10

Single- and multiple-dose pharmacokinetics of arginase inhibitor Nω-hydroxy-nor-L-arginine, and its effect on plasma amino acids concentrations in Wistar rats

Havlínová, Zuzana, Hroch, Miloš, Nagy, Andrea, Šišpera, Luděk, Holeček, Milan, Chládek, Jaroslav

Journal:

General Physiology and Biophysics

Year:

2014

Language:

english

File:

PDF, 852 KB

english, 2014

11

Evaluation of Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Glomerular Filtration Rate and Amikacin Clearance During Early Rat Endotoxemia: Comparison with Traditional Endogenous and Exogenous Biomarkers

Studená, Šárka, Doleželová, Eva, Cermanová, Jolana, Prašnická, Alena, Springer, Drahomíra, Mičuda, Stanislav, Chládek, Jaroslav

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2019

Language:

english

File:

PDF, 897 KB

english, 2019

12

Plasmafiltration as an effective method in the removal of circulating pegylated liposomal doxorubicin (PLD) and the reduction of mucocutaneous toxicity during the treatment of advanced platinum-resistant ovarian cancer

Kubeček, Ondřej, Martínková, Jiřina, Chládek, Jaroslav, Bláha, Milan, Maláková, Jana, Hodek, Miroslav, Špaček, Jiří, Filip, Stanislav

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2019

Language:

english

File:

PDF, 870 KB

english, 2019

13

Alveolar concentration and bronchial flux of nitric oxide: Two linear modeling methods evaluated in children and adolescents with allergic rhinitis and atopic asthma

Jirina Chládková, Marian Senkerík, Zuzana Havlínová, Irena Krcmová, Jaroslav Chládek

Journal:

Pediatric Pulmonology

Year:

2012

Language:

english

File:

PDF, 222 KB

english, 2012

14

Analysis of Single-breath Profiles of Exhaled Nitric Oxide in Children with Allergy and Asthma: Guideline-derived Plateau Concentrations Compared to Results of Automatic Evaluation by Two Analyzers

Chládková, Jirina, Havlínová, Zuzana, Chyba, Tomás, Krcmová, Irena, Chládek, Jaroslav

Journal:

Journal of Asthma

Year:

2008

Language:

english

File:

PDF, 914 KB

english, 2008

15

Urinary N-acetyl-β-D-glucosaminidase activity in healthy children

SYLVA SKÁLOVÁ, JAROSLAV CHLÁDEK

Journal:

Year:

2004

Language:

english

File:

PDF, 58 KB

english, 2004

16

Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart

Jirkovsky, Eduard, Jirkovska, Anna, Bures, Jan, Chladek, Jaroslav, Lencova, Olga, Stariat, Jan, Pokorna, Zuzana, Karabanovich, Galina, Roh, Jaroslav, Brazdova, Petra, Simunek, Tomas, Kovarikova, Petra

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

17

Amiodarone modulates pharmacokinetics of low-dose methotrexate in rats

Leos Fuksa, Eva Brcakova, Jolana Cermanova, Milos Hroch, Jaroslav Chladek, Gabriela Kolouchova, Jana Malakova, Jirina Martinkova, Frantisek Staud, Stanislav Micuda

Journal:

Biopharmaceutics & Drug Disposition

Year:

2008

Language:

english

File:

PDF, 128 KB

english, 2008

18

Hyaluronidase: Its effects on HI-6 dichloride and dimethanesulphonate pharmacokinetic profile in pigs

Karasova, Jana Zdarova, Pavlik, Michal, Chladek, Jaroslav, Jun, Daniel, Kuca, Kamil

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 419 KB

english, 2013

19

Health aspects of burning coal with a high arsenic content: II. Hearing changes in exposed children

Vladimír Bencko, Karel Symon, Vladimír Chládek, Jaroslav Pihrt

Journal:

Environmental Research

Year:

1977

Language:

english

File:

PDF, 565 KB

english, 1977

20

Free 3-nitrotyrosine in exhaled breath condensates of children fails as a marker for oxidative stress in stable cystic fibrosis and asthma

Silva Celio, Heinz Troxler, Silke S. Durka, Jaroslav Chládek, Johannes H. Wildhaber, Felix H. Sennhauser, Claus W. Heizmann, Alexander Moeller

Journal:

Year:

2006

Language:

english

File:

PDF, 215 KB

english, 2006

21

Intra-individual variability and influence of urine collection period on dextromethorphan metabolic ratios in healthy subjects

Jaroslav Chládek, Gabriela Zimová, Jirina Martínková, Ivan Tůma

Journal:

Fundamental & Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 662 KB

english, 1999

22

Low-Dose Methotrexate Pharmacokinetics and Pharmacodynamics in the Therapy of Severe Psoriasis

Jaroslav Chladek, Jiri Grim, Jirina Martinkova, Marie Simkova, Jaroslava Vaneckova

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2005

Language:

english

File:

PDF, 46 KB

english, 2005

23

Pharmacokinetic study of two acetylcholinesterase reactivators, trimedoxime and newly synthesized oxime K027, in rat plasma

Jana Zdarova Karasova, Jaroslav Chladek, Milos Hroch, Fusek Josef, Daniela Hnidkova, Kamil Kuca

Journal:

Journal of Applied Toxicology

Year:

2012

Language:

english

File:

PDF, 274 KB

english, 2012

24

Oxidative stress in cystic fibrosis patients withBurkholderia cenocepaciaairway colonization: relation of 8-isoprostane concentration in exhaled breath condensate to lung function decline

Fila, Libor, Grandcourtová, Alžběta, Chládek, Jaroslav, Musil, Jaromír

Journal:

Folia Microbiologica

Year:

2014

Language:

english

File:

PDF, 358 KB

english, 2014

25

HPLC determination of arginases inhibitor N-(ω)-hydroxy-nor-l-arginine using core–shell particle column and LC–MS/MS identification of principal metabolite in rat plasma

Miloš Hroch, Zuzana Havlínová, Milan Nobilis, Jaroslav Chládek

Journal:

Journal of Chromatography B

Year:

2012

Language:

english

File:

PDF, 352 KB

english, 2012

26

Activation of p38 MAPK and expression of TGF-β1 in rat colon enterocytes after whole body γ-irradiation

Pejchal, Jaroslav, Novotný, Jakub, Mařák, Václav, Österreicher, Jan, Tichý, Aleš, Vávrová, Jiřina, Šinkorová, Zuzana, Zárybnická, Lenka, Novotná, Eva, Chládek, Jaroslav, Babicová, Andrea, Kubelková, K

Journal:

International Journal of Radiation Biology

Year:

2012

Language:

english

File:

PDF, 740 KB

english, 2012

27

Erratum to: Kinetically Guided Neoadjuvant Chemoradiotherapy Based on 5-Fluorouracil in Patients with Locally Advanced Rectal Cancer

Grim, Jiří, Hroch, Miloš, Chládek, Jaroslav, Petera, Jiří, Martínková, Jiřina

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 126 KB

english, 2015

28

Validation of Nitrite and Nitrate Measurements in Exhaled Breath Condensate

Chladkova, Jirina, Krcmova, Irena, Chladek, Jaroslav, Cap, Petr, Micuda, Stanislav, Hanzalkova, Yvona

Journal:

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

29

High-performance liquid chromatographic assay for the determination of 5-methyltetrahydrofolate in human plasma

Jaroslav Chládek, Luděk Šišpera, Jiřina Martı́nková

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

30

A comparative study of pharmacokinetics, urinary excretion and tissue distribution of platinum in rats following a single-dose oral administration of two platinum(IV) complexes LA-12 (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV) and satraplatin (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum(IV)

Petr Sova, Adolf Mistr, Ales Kroutil, Martin Semerád, Hana Chlubnová, Veronika Hrusková, Jirina Chládková, Jaroslav Chládek

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 464 KB

english, 2011

31

Kinetically Guided Neoadjuvant Chemoradiotherapy Based on 5-Fluorouracil in Patients with Locally Advanced Rectal Cancer

Grim, Jiří, Miloš, Hroch, Jaroslav, Chládek, Jiří, Petera, Jiřina, Martínková

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

32

IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats

Kadova, Zuzana, Dolezelova, Eva, Cermanova, Jolana, Hroch, Milos, Laho, Tomas, Muchova, Lucie, Staud, Frantisek, Vitek, Libor, Mokry, Jaroslav, Chladek, Jaroslav, Havlinova, Zuzana, Holecek, Milan, Mi

Journal:

AJP: Renal Physiology

Year:

2015

Language:

english

File:

PDF, 834 KB

english, 2015

33

Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats

Prasnicka, Alena, Cermanova, Jolana, Hroch, Milos, Dolezelova, Eva, Rozkydalova, Lucie, Smutny, Tomas, Carazo, Alejandro, Chladek, Jaroslav, Lenicek, Martin, Nachtigal, Petr, Vitek, Libor, Pavek, Petr

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

34

Pharmacokinetics and pharmacodynamics of low-dose methotrexate in the treatment of psoriasis

Jaroslav Chládek, Jiøı´ Grim, Jiøina Martínková, Marie Šimková, Jaroslava Vanı`èková, Vı`ra Koudelková, Marie Noièková

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 152 KB

english, 2002

35

Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions

Stanislav Micuda, Lucie Mundlova, Eva Anzenbacherova, Pavel Anzenbacher, Jaroslav Chladek, Leos Fuksa, Jirina Martinkova

Journal:

European Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 241 KB

english, 2004

36

The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis

Jaroslav Chládek, Marie Simková, Jaroslava Vanecková, Milos Hroch, Jirina Chládkova, Jirina Martínková, Jaroslava Vávrová, Martin Beránek

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

37

Early changes in L-arginine-nitric oxide metabolic pathways in response to the whole-body gamma irradiation of rats

Babicova, Andrea, Havlinova, Zuzana, Pejchal, Jaroslav, Tichy, Ales, Rezacova, Martina, Vavrova, Jirina, Chladek, Jaroslav

Journal:

International Journal of Radiation Biology

Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

38

Comparative pharmacokinetics of N ω -hydroxy-nor-L-arginine, an arginase inhibitor, after single-dose intravenous, intraperitoneal and intratracheal administration to brown Norway rats

Havlinova, Zuzana, Babicova, Andrea, Hroch, Milos, Chladek, Jaroslav

Journal:

Year:

2013

Language:

english

File:

PDF, 422 KB

english, 2013

39

Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane

Lenčová-Popelová, Olga, Jirkovský, Eduard, Jansová, Hana, Jirkovská-Vávrová, Anna, Vostatková-Tichotová, Lucie, Mazurová, Yvona, Adamcová, Michaela, Chládek, Jaroslav, Hroch, Miloš, Pokorná, Zuzana, G

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2016

Language:

english

File:

PDF, 2.52 MB

english, 2016

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